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Hybridization is a basic property of nucleotide sequences and is taken advantage of in numerous molecular biology techniques. Overall, genetic relatedness of two species can be determined by hybridizing segments of their DNA (DNA-DNA hybridization). Due to sequence similarity between closely related organisms, higher temperatures are required ...
Genetic complementation is a hybridization test widely used in genetics to determine whether two separately isolated mutants that have the same (or similar) phenotype are defective in the same gene or in different genes (see complementation). [26]
Introgression, also known as introgressive hybridization, in genetics is the transfer of genetic material from one species into the gene pool of another by the repeated backcrossing of an interspecific hybrid with one of its parent species. Introgression is a long-term process, even when artificial; it may take many hybrid generations before ...
Introgressive hybridization - hybridization resulting in the transfer of a gene or genetic tract from one species into the gene pool of another species by repeated backcrossing. Intrinsic incompatibilities - environment-independent reproductive barriers.
Reproductive isolation may be genetic, ecological, [5] behavioral, spatial, or a combination of these. If reproductive isolation fails to establish, the hybrid population may merge with either or both parent species. This will lead to an influx of foreign genes into the parent population, a situation called an introgression. Introgression is a ...
In genomics, DNA–DNA hybridization is a molecular biology technique that measures the degree of genetic similarity between DNA sequences. It is used to determine the genetic distance between two organisms and has been used extensively in phylogeny and taxonomy .
General process of fluorescent in situ hybridization (FISH) used for bacterial pathogen identification. First, an infected tissue sample is taken from the patient. Then an oligonucleotide complementary to the suspected pathogen's genetic code is chemically tagged with a fluorescent probe.
Genetic alterations and rearrangements occur frequently in cancer and contribute to its pathogenesis. Detecting these aberrations by array CGH provides information on the locations of important cancer genes and can have clinical use in diagnosis, cancer classification and prognostification. [17]