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The Z-score for bone density is the comparison to the "age-matched normal" and is usually used in cases of severe osteoporosis. This is the standard score or number of standard deviations a patient's bone mineral density differs from the average for their age, sex, and ethnicity.
Quantitative computed tomography (QCT) differs from DXA in that it gives separate estimates of BMD for trabecular and cortical bone and reports precise volumetric mineral density in mg/cm 3 rather than BMD's relative Z-score. Among QCT's advantages: it can be performed at axial and peripheral sites, can be calculated from existing CT scans ...
Bone densities are often given to patients as a T score or a Z score. A T score tells the patient what their bone mineral density is in comparison to a young adult of the same gender with peak bone mineral density. A normal T score is -1.0 and above, low bone density is between -1.0 and -2.5, and osteoporosis is -2.5 and lower.
The BMD is corrected for porosity of the bone, estimated by a texture analysis performed on the cortical part of the bone. [2] [3] Like other technologies for estimating the bone mineral density, the outputs are an areal BMD value, a T-score and a Z-score for assessing osteoporosis and the risk of bone fracture. [4]
At the hip, a DXA-equivalent T-score may be calculated for comparison to the WHO classification at the proximal femur as normal, osteopenia (T-Score < -1.0 and > -2.5) or osteoporosis (T-Score < -2.5). [17] This T-Score may also be used for fracture risk probability calculation in the WHO FRAX tool [18] with "T-Score" as the appropriate DXA ...
Osteopenia, known as "low bone mass" or "low bone density", is a condition in which bone mineral density is low. [1] Because their bones are weaker, people with osteopenia may have a higher risk of fractures , and some people may go on to develop osteoporosis . [ 2 ]