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Epileptogenesis is the gradual process by which a typical brain develops epilepsy. [1] Epilepsy is a chronic condition in which seizures occur. [2] These changes to the brain occasionally cause neurons to fire in an abnormal, hypersynchronous manner, known as a seizure. [3]
The reason this occurs in most cases of epilepsy is unknown (cryptogenic); [1] some cases occur as the result of brain injury, stroke, brain tumors, infections of the brain, or birth defects through a process known as epileptogenesis. [1] [2] [3] Known genetic mutations are directly linked to a small proportion of cases.
Systemic infection with high fever is a common cause of seizures, especially in children. [3] [25] These are called febrile seizures and occur in 2–5% of children between the ages of six months and five years. [26] [25] Acute infection of the brain, such as encephalitis or meningitis are also causes of seizures. [3]
A seizure is a paroxysmal episode of symptoms or altered behavior arising from abnormal excessive or synchronous brain neuronal activity. [5] A focal onset seizure arises from a biological neural network within one cerebral hemisphere, while a generalized onset seizure arises from within the cerebral hemispheres rapidly involving both hemispheres.
There are many causes of seizures. Organ failure, medication and medication withdrawal, cancer, imbalance of electrolytes, hypertensive encephalopathy , may be some of its potential causes. [ 2 ] The factors that lead to a seizure are often complex and it may not be possible to determine what causes a particular seizure, what causes it to ...
Heart disease. High blood pressure (hypertension) Type 2 diabetes. Stroke. Obesity. What insomnia treatments are available? When it comes to how to treat insomnia, there are several treatment ...
However, the most common mechanical models of traumatic brain injury such as fluid percussion injury, controlled cortical impact, and weight-drop injury models exhibit epileptogenesis at chronic time points with documented remote electroencephalographic and behavioral seizures, and increased seizure susceptibility. [43]
A new review reports that nine people taking semaglutide and tirzepatide — the active ingredient in GLP-1 medications — experienced vision issues, including three potentially blinding eye ...