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Cryoprecipitate, also called cryo for short, or Cryoprecipitate Antihemophilic factor (AHF), is a frozen blood product prepared from blood plasma. [1] To create cryoprecipitate, Plasma is slowly thawed to 1–6 °C. A cold-insoluble precipitate is formed, which is collected by centrifugation, resuspended in a small amount of residual plasma ...
The term cryosupernatant (also called cryo-poor plasma, cryoprecipitate depleted, cryoprecipitate reduced plasma) refers to plasma from which the cryoprecipitate has been removed. It is used to treat thrombocytopenic purpura .
It is used in the treatment of massive bleeding, in exchange transfusion, and when people donate blood to themselves (autologous transfusion). [1] [2] One unit of whole blood (approximately 450 mL) increases hemoglobin levels by about 10 g/L. [3] [4] Cross matching is typically done before the blood is given. [2] [5] It is given by injection ...
Transfusion associated circulatory overload (TACO) is a common, yet underdiagnosed, reaction to blood product transfusion consisting of the new onset or exacerbation of three of the following within 6 hours of cessation of transfusion: acute respiratory distress, elevated brain natriuretic peptide (BNP), elevated central venous pressure (CVP ...
Since it is time-consuming to find compatible donors for HLA-matched transfusions, collecting a full dose from a single donor is more practical than finding multiple compatible donors. [citation needed] Plateletpheresis products are also easier to test for bacterial contamination, a leading cause of transfusion-associated deaths.
Red blood cell concentrates, also known as red cell concentrates or packed red blood cells, are red blood cells that have been separated for blood transfusion. [1] A red blood cell concentrate typically has a haematocrit of 0.50 – 0.70 L/L and a volume between 250 and 320 mL.
Colloids preserve a high colloid osmotic pressure in the blood, while, on the other hand, this parameter is decreased by crystalloids due to hemodilution. [11] Therefore, they should theoretically preferentially increase the intravascular volume , whereas crystalloids also increase the interstitial volume and intracellular volume .
The severity and prognosis of acute hemolytic transfusion depends on the rate of blood administration and the total volume of the transfusion. The levels of anti-A and anti-B antibodies in the recipients blood may also predict the prognosis, with higher levels of antibodies thought to portend a more severe course. [ 6 ]