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Death rate from obesity, 2019. Obesity is a risk factor for many chronic physical and mental illnesses.. The health effects of being overweight but not obese are controversial, with some studies showing that the mortality rate for individuals who are classified as overweight (BMI 25.0 to 29.9) may actually be lower than for those with an ideal weight (BMI 18.5 to 24.9). [1]
The Women's Health Initiative (WHI) was a series of clinical studies initiated by the U.S. National Institutes of Health (NIH) in 1991, to address major health issues causing morbidity and mortality in postmenopausal women. It consisted of three clinical trials (CT) and an observational study (OS).
As a result of pressure from HIV-infected men in the gay community, [citation needed] who demanded better access to clinical trials, the U.S. Congress passed the Health Omnibus Programs Extension Act of 1988 (Public Law 100-607) [2] which mandated the development of a database of AIDS Clinical Trials Information Services (ACTIS). [3]
Despite representing 50% of the U.S. population, women are generally underrepresented in clinical trials. For example, women represent 38.2% of participants in cardiovascular clinical trials. When ...
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Both overweight and obesity are major risk factors for cardiovascular diseases, specifically heart disease and stroke, and diabetes. The International Diabetes Federation reports that as of 2011 [needs update], 366 million people have diabetes; this number is projected to increase to over half a billion (estimated 552 million) by 2030.