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Liver failure; Pancreatitis (these two usually occur in first 6 months and can be fatal) Leukopenia (low white blood cell count) Neutropenia (low neutrophil count) Pure red cell aplasia; Agranulocytosis; Extrapyramidal syndrome (including parkinsonism, may be reversible) Brain problems due to high ammonia levels; Low body temperature
Liver injury; Gastralgia; Diarrhoea; Extrapyramidal (movement) disorder; Stupor [a] Somnolence; Convulsion [a] Memory impairment; Headache; Nystagmus; Confusional state; Aggression [b] Agitation [b] Impaired attention [b] Hyponatraemia; Anaemia; Thrombocytopaenia; Hypersensitivity; Transient and/or dose-related hair loss; Dysmenorrhea ...
Common side effects of valproate include nausea, vomiting, somnolence, and dry mouth. [7] Serious side effects can include liver failure, and regular monitoring of liver function tests is therefore recommended. [7] Other serious risks include pancreatitis and an increased suicide risk. [7]
Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances, both toxic chemicals and medications, on kidney function. [1] There are various forms, [2] and some drugs may affect kidney function in more than one way. Nephrotoxins are substances displaying nephrotoxicity.
Typical regimens included stimulants, such as amphetamines, as well as thyroid hormone, diuretics, digitalis, laxatives, and often a barbiturate to suppress the side effects of the stimulants. [38] In 1967/1968 a number of deaths attributed to diet pills triggered a Senate investigation and the gradual implementation of greater restrictions on ...
Liver failure is the inability of the liver to perform its normal synthetic and metabolic functions as part of normal physiology. Two forms are recognised, acute and chronic (cirrhosis). [ 1 ] Recently, a third form of liver failure known as acute-on-chronic liver failure ( ACLF ) is increasingly being recognized.
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