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  2. IgG deficiency - Wikipedia

    en.wikipedia.org/wiki/IgG_deficiency

    IgG deficiency is a form of dysgammaglobulinemia where the proportional levels of the IgG isotype are reduced relative to other immunoglobulin isotypes.. IgG deficiency is often found in children as transient hypogammaglobulinemia of infancy, which may occur with or without additional decreases in IgA or IgM.

  3. DOCK8 deficiency - Wikipedia

    en.wikipedia.org/wiki/DOCK8_deficiency

    The signs and symptoms of DOCK8 deficiency are similar to the autosomal dominant form, STAT3 deficiency. However, in DOCK8 deficiency, there is no skeletal or connective tissue involvement, and affected individuals do not have the characteristic facial features of those with autosomal dominant hyper-IgE syndrome.

  4. Immunoglobulin E - Wikipedia

    en.wikipedia.org/wiki/Immunoglobulin_E

    IgE was simultaneously discovered in 1966 and 1967 by two independent groups: [12] by Kimishige Ishizaka and his wife Teruko Ishizaka at the Children's Asthma Research Institute and Hospital in Denver, Colorado, [13] and by Gunnar Johansson and Hans Bennich in Uppsala, Sweden. [14] Their joint paper was published in April 1969. [15]

  5. Asthma - Wikipedia

    en.wikipedia.org/wiki/Asthma

    Asthma phenotyping and endotyping has emerged as a novel approach to asthma classification inspired by precision medicine which separates the clinical presentations of asthma, or asthma phenotypes, from their underlying causes, or asthma endotypes. The best-supported endotypic distinction is the type 2-high/type 2-low distinction.

  6. Allergy - Wikipedia

    en.wikipedia.org/wiki/Allergy

    Quantitative IgE test results increase the possibility of ranking how different substances may affect symptoms. A rule of thumb is that the higher the IgE antibody value, the greater the likelihood of symptoms. Allergens found at low levels that today do not result in symptoms cannot help predict future symptom development.

  7. Allergic inflammation - Wikipedia

    en.wikipedia.org/wiki/Allergic_inflammation

    Allergic inflammation is an important pathophysiological feature of several disabilities or medical conditions including allergic asthma, atopic dermatitis, allergic rhinitis and several ocular allergic diseases. Allergic reactions may generally be divided into two components; the early phase reaction, and the late phase reaction.

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