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Additive genetic effects occur where expression of more than one gene contributes to phenotype (or where alleles of a heterozygous gene both contribute), and the phenotypic expression of these gene (s) can be said to be the sum of these contributions. Non-additive effects involve dominance or epistasis, and cause outcomes that are not a sum of ...
The ACE model is a statistical model commonly used to analyze the results of twin and adoption studies. This classic behaviour genetic model aims to partition the phenotypic variance into three categories: additive genetic variance (A), common (or shared) environmental factors (C), and specific (or nonshared) environmental factors plus ...
Genetic variance has three major components: the additive genetic variance, dominance variance, and epistatic variance. [3] Additive genetic variance involves the inheritance of a particular allele from your parent and this allele's independent effect on the specific phenotype, which will cause the phenotype deviation from the mean phenotype.
In statistical genetics, inclusive composite interval mapping (ICIM) has been proposed as an approach to QTL (quantitative trait locus) mapping for populations derived from bi-parental crosses. QTL mapping is based on genetic linkage map and phenotypic data to attempt to locate individual genetic factors on chromosomes and to estimate their ...
Gene–environment interaction. Gene–environment interaction (or genotype–environment interaction or G×E) is when two different genotypes respond to environmental variation in different ways. A norm of reaction is a graph that shows the relationship between genes and environmental factors when phenotypic differences are continuous. [1]
Polygene. A polygene is a member of a group of non- epistatic genes that interact additively to influence a phenotypic trait, thus contributing to multiple-gene inheritance (polygenic inheritance, multigenic inheritance, quantitative inheritance[1]), a type of non-Mendelian inheritance, as opposed to single-gene inheritance, which is the core ...
An ADE model is a genetic model for twin studies which includes dominance genetic effects. [1] A stands for additive genetic effects, D for non-additive genetic (or dominance) effects, and E for nonshared environment effects.
Fisher's fundamental theorem of natural selection is an idea about genetic variance [1][2] in population genetics developed by the statistician and evolutionary biologist Ronald Fisher. The proper way of applying the abstract mathematics of the theorem to actual biology has been a matter of some debate, however, it is a true theorem. [3]