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  2. Chloroquine retinopathy - Wikipedia

    en.wikipedia.org/wiki/Chloroquine_retinopathy

    Chloroquine retinopathy is a form of toxic retinopathy (damage of the retina) caused by the drugs chloroquine or hydroxychloroquine, which are sometimes used in the treatment of autoimmune disorders such as rheumatoid arthritis and systemic lupus erythematosus. This eye toxicity limits long-term use of the drugs. [3]

  3. Hydroxychloroquine - Wikipedia

    en.wikipedia.org/wiki/Hydroxychloroquine

    Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth, often in the form of hydroxychloroquine sulfate. [3] Common side effects may include vomiting, headache, blurred vision, and muscle weakness. [3] Severe side effects may include allergic reactions, retinopathy, and irregular heart rate.

  4. Combined drug intoxication - Wikipedia

    en.wikipedia.org/wiki/Combined_drug_intoxication

    Alcohol can exacerbate the symptoms and may directly contribute to increased severity of symptoms. The reasons for toxicity vary depending on the mixture of drugs. Usually, most victims die after using two or more drugs in combination that suppress breathing, and the low blood oxygen level causes brain death.

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  6. Chloroquine - Wikipedia

    en.wikipedia.org/wiki/Chloroquine

    Serious side effects include problems with vision, muscle damage, seizures, and low blood cell levels. [ 1 ] [ 4 ] Chloroquine is a member of the drug class 4-aminoquinoline . [ 1 ] As an antimalarial, it works against the asexual form of the malaria parasite in the stage of its life cycle within the red blood cell . [ 1 ]

  7. Adverse drug reaction - Wikipedia

    en.wikipedia.org/wiki/Adverse_drug_reaction

    Type A: augmented pharmacological effects, which are dose-dependent and predictable [5]; Type A reactions, which constitute approximately 80% of adverse drug reactions, are usually a consequence of the drug's primary pharmacological effect (e.g., bleeding when using the anticoagulant warfarin) or a low therapeutic index of the drug (e.g., nausea from digoxin), and they are therefore predictable.

  8. Pharmacotoxicology - Wikipedia

    en.wikipedia.org/wiki/Pharmacotoxicology

    In this case, both the therapeutic and toxic targets are the same. To avoid toxicity during treatment, many times the drug needs to be changed to target a different aspect of the illness or symptoms. Statins are an example of a drug class that can have toxic effects at the therapeutic target (HMG CoA reductase). [1]

  9. Tricyclic antidepressant overdose - Wikipedia

    en.wikipedia.org/wiki/Tricyclic_antidepressant...

    TCA poisoning, TCA overdose, TCA toxicity: Chemical structure of the tricyclic antidepressant amitriptyline: Specialty: Emergency medicine: Symptoms: Elevated body temperature, large pupils, irregular heart beat, seizures [1] Usual onset: Within 6 hours [2] Causes: Accidental or purposeful [2] [3] Treatment: Supportive, sodium bicarbonate ...