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Diphenhydramine is contraindicated in premature infants and neonates, as well as people who are breastfeeding. It is a pregnancy Category B drug. Diphenhydramine has additive effects with alcohol and other CNS depressants. Monoamine oxidase inhibitors prolong and intensify the anticholinergic effect of antihistamines. [50]
Common side effects include blurred vision, dry mouth, sleepiness, constipation, and confusion. [2] It should not be used in people with a bowel obstruction or glaucoma. [2] It is unclear if use in pregnancy or breastfeeding is safe. [4] Biperiden is in the anticholinergic family of medication. [2]
Breastfeeding and medications is the description of the medications that can be used by a breastfeeding mother, and the balance between maternal health and the safety of the breastfeeding infant. [ 1 ] [ 2 ] Medications, when administered to breastfeeding mothers, almost always are transferred to breast milk, albeit usually in small quantities ...
Benadryl can also be found in a topical form including gels and creams. Benadryl Itch Stopping Cream is a topical cream used to provide temporary itch relief for allergies, hives or even some insect bites. It can be found in the United States and Canada. This topical medication contains 2% of diphenhydramine hydrochloride and 1% of zinc acetate.
In July 1975, the J. B. Williams Co. began marketing Sominex 2. [37] On November 24, 1975, Attorney General Evelle J. Younger filed suit on behalf of the State of California against Williams Co., stating that the product did not warn against use by pregnant or nursing women or persons with asthma or COPD, nor did it notify consumers that it should not be used in conjunction with alcohol. [38]
Effects generally begin within thirty minutes and last for about a day. [12] The degree of benefit is similar to other antihistamines such as diphenhydramine, which is a first-generation antihistamine. [12] Common side effects include sleepiness, dry mouth, headache, and abdominal pain. [12]
Midol, like other NSAID class of drugs, may have side effects for some, such as an increased risk of bleeding, kidney damage or negative effects on cardiovascular system. [7] The "Midol Complete" formulation consists of: Acetaminophen 500 mg (pain reliever) Caffeine 60 mg (stimulant) Pyrilamine maleate 15 mg (antihistamine)
Side effects [ edit ] Continuous and/or cumulative use of anticholinergic medications, including first-generation antihistamines, is associated with higher risk for cognitive decline and dementia in elderly people.