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Darier's sign is a change observed after stroking lesions on the skin of a person with systemic mastocytosis or urticaria pigmentosa. [1] In general, the skin becomes swollen, itchy and red. This is a result of compression of mast cells, which are hyperactive in these diseases. These mast cells release inflammatory granules which contain ...
Management and treatment of Darier disease depends on the severity of the presented clinical symptoms. Mild symptoms are often treated with moisturising creams, and more severe symptoms with topical and oral retinol or other medications (oral medications having higher strength than topical equivalents), and medical procedures.
The evaluation strategy should take into account diagnosing the underlying condition, perhaps treating the longitudinal erythronychia adequately, and trying to reduce the risk of any procedure-related consequences. The clinical history can be useful in explaining symptoms that could point to a glomus tumor.
It was first described by Darier in 1916. [3] [4] [5] Many different terms have been used to classify these types of lesions and it is still controversial on what exactly defines EAC. Some of the types include annular erythema (deep and superficial), erythema perstans, erythema gyratum perstans, erythema gyratum repens, darier erythema (deep ...
These mast cells, when irritated (e.g. by rubbing the skin, heat exposure), produce too much histamine, triggering an allergic reaction that leads to hives localized to the area of irritation, sometimes referred to as Darier's sign. Severe itching usually follows, and scratching the area only serves to further symptoms.
1.symptoms associated with hypoglycaemia 2. measured low serum glucose 3. relief of symptoms with administration of glucose p.o. or iv Wickham's striae: Louis Frédéric Wickham: dermatology: lichen planus: white or greyish lines on the lichen planus lesions Widal test: Georges-Fernand Widal: microbiology: enteric fever: serum agglutination ...
A Chinese pain scale diagram, rating pain on a scale of 1 to 10. A pain scale measures a patient's pain intensity or other features. Pain scales are a common communication tool in medical contexts, and are used in a variety of medical settings. Pain scales are a necessity to assist with better assessment of pain and patient screening.
Onychauxis presents with thickened nails without deformity, and this simple thickening may be the result of trauma, acromegaly, Darier's disease, psoriasis, or pityriasis rubra pilaris, or, in some cases, hereditary. [1]: 783 [2] It may appear as loss of nail palate translucency, discoloration, and subungual hyperkeratosis.