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Paget's disease of bone is the second most common metabolic bone disorder, after osteoporosis. [37] The overall prevalence and severity of Paget's disease are decreasing; the cause for these changes is unclear. [38] Paget's disease is rare in people less than 55 years of age, [7] and the prevalence increases with age. [38]
Paget's disease of the breast (also known as mammary Paget's disease) is a rare skin change at the nipple nearly always associated with underlying breast cancer. [2] Paget's disease of the breast was first described by Sir James Paget in 1874. [3] The condition is an uncommon disease accounting for 1 to 4% of all breast cancers cases.
The Guideline Development Group then finalises the recommendations and the National Collaboration Centre produces the final guideline. This is submitted to NICE to formally approve the guideline and issue the guidance to the NHS. [citation needed] To date NICE has produced more than 200 different guidelines. [27]
Paget's disease may refer to several conditions described by Sir James Paget, surgeon and pathologist: Paget's disease of bone (most common use of the term "Paget's disease") Paget's disease of the breast; Paget–Schroetter disease; Paget's abscess; Extramammary Paget's disease (EMPD)
There are many bone disorders such as osteoporosis, Paget's disease, hypothyroidism. [2] Although there are many forms of bone disorders, they all have one thing in common; abnormalities of specific organs involved, deficiency in vitamin D or low Calcium in diet, which results in poor bone mineralization .
A Paget's abscess, named by eminent British surgeon and pathologist Sir James Paget, is an abscess that recurs at the site of a former abscess which had resolved. [1] [2]
Extramammary Paget's disease (EMPD) is a rare and slow-growing cancer, which occurs within the epithelial tissues [1] and accounts for 6.5% of all Paget's disease. [2] This disease presents similarly to the more conventional form of mammary Paget's disease (MPD). [ 3 ]
In suggesting this painting depicted someone suffering from Paget's disease, Mr. Baum neglected to note that it was a caricature, not a work of realist portraiture. — Preceding unsigned comment added by 162.72.159.156 ( talk ) 05:03, 1 June 2013 (UTC) [ reply ]