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The current Rome IV classification [22] is the culmination of the evolution of a series of iterations (Rome I, [19] Rome II, [27] and Rome III [28]) with its inception as Rome I. [19] The Rome criteria are a set of criteria used by clinicians to classify a diagnosis of a patient with an FGID (disorder of gut-brain interaction).
The consensus review process of meetings and publications organised by the Rome Foundation, known as the Rome process, has helped to define the functional gastrointestinal disorders. [3] Successively, the Rome I, Rome II, Rome III and Rome IV proposed consensual classification system and terminology, as recommended by the Rome Coordinating ...
The Rome IV criteria further classifies functional dyspepsia into two subtypes, postprandial distress syndrome (PDS) and epigastric pain syndrome (EPS). [54] Postprandial distress syndrome is marked by dyspeptic symptoms brought on by meals, such as postprandial fullness and early satiety and accounts for 69% of patients with functional dyspepsia.
The Rome IV criteria for diagnosing IBS include recurrent abdominal pain, on average, at least one day/week in the last three months, associated with additional stool- or defecation-related criteria. [73] The algorithm may include additional tests to guard against misdiagnosis of other diseases as IBS.
To qualify for this diagnosis, patients must meet the Rome diagnostic criteria for functional constipation or irritable bowel syndrome with constipation (IBS-C). [32] Furthermore, 2 of the following 3 tests must show abnormal results: balloon expulsion test, anorectal manometry or anal surface electromyography, or imaging (e.g. defecography). [32]
The Manning criteria have been compared with other diagnostic algorithms for IBS, such as the Rome I criteria, the Rome II process, and the Kruis criteria. [2] A 2013 validation study found the Manning criteria to have less sensitivity but more specificity than the Rome criteria. [3]