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  2. Granulomatosis with polyangiitis - Wikipedia

    en.wikipedia.org/wiki/Granulomatosis_with...

    Granulomatosis with polyangiitis is part of a larger group of vasculitic syndromes called systemic vasculitides or necrotizing vasculopathies, all of which feature an autoimmune attack by an abnormal type of circulating antibody termed ANCAs (antineutrophil cytoplasmic antibodies) against small and medium-sized blood vessels.

  3. Eosinophilic granulomatosis with polyangiitis - Wikipedia

    en.wikipedia.org/wiki/Eosinophilic...

    Eosinophilic granulomatosis with polyangiitis consists of three stages, but not all patients develop all three stages or progress from one stage to the next in the same order; [7] whereas some patients may develop severe or life-threatening complications such as gastrointestinal involvement and heart disease, some patients are only mildly affected, e.g. with skin lesions and nasal polyps. [8]

  4. Azathioprine - Wikipedia

    en.wikipedia.org/wiki/Azathioprine

    Azathioprine, sold under the brand name Imuran, among others, is an immunosuppressive medication. [5] It is used for the treatment of rheumatoid arthritis, granulomatosis with polyangiitis, Crohn's disease, ulcerative colitis, and systemic lupus erythematosus, and in kidney transplants to prevent rejection.

  5. Overlap syndrome - Wikipedia

    en.wikipedia.org/wiki/Overlap_syndrome

    The term polyangiitis overlap syndrome refers to a systemic vasculitis that shares features with two or more distinct vasculitis syndromes. The most common type of polyangiitis overlap syndrome is microscopic polyangiitis (MPA), which shares features with EGPA, granulomatosis with polyangiitis and panarteritis nodosa .

  6. p-ANCA - Wikipedia

    en.wikipedia.org/wiki/P-ANCA

    p-ANCA is associated with several medical conditions: [3] It is fairly specific, but not sensitive for ulcerative colitis, so is not useful as a sole diagnostic test. [4] When measured together with anti-saccharomyces cerevisiae antibodies (ASCA), p-ANCA has been estimated to have a specificity of 97% and a sensitivity of 48% in differentiating patients with ulcerative colitis from normal ...

  7. Palisaded neutrophilic and granulomatous dermatitis - Wikipedia

    en.wikipedia.org/wiki/Palisaded_neutrophilic_and...

    Palisaded neutrophilic and granulomatous dermaititis is associated with subacute bacterial endocarditis, [4] ledipasvir/sofosbuvir, [5] allopurinol, [6] Hodgkin’s and non-Hodgkin’s lymphoma, [4] chronic myelomonocytic leukemia, [7] ulcerative colitis, [8] Takayasu arteritis, [4] systemic vasculitis, [8] systemic lupus erythematosus (SLE), [9] sarcoidosis, [10] rheumatoid arthritis, [11 ...

  8. Pauci-immune - Wikipedia

    en.wikipedia.org/wiki/Pauci-immune

    The negative immunofluorescence pattern, however, is called "pauci-immune" and is often associated with systemic vasculitides (plural of vasculitis) including: microscopic polyangiitis, eosinophilic granulomatosis with polyangiitis (EGPA), and granulomatosis with polyangiitis (GPA). [1] [2]

  9. Rapidly progressive glomerulonephritis - Wikipedia

    en.wikipedia.org/wiki/Rapidly_progressive_glomer...

    Type III RPGN may be isolated to the glomerulus (primary, or idiopathic) or associated with a systemic disease (secondary). In most cases of the latter, the systemic disease is an ANCA-associated vasculitis such as granulomatosis with polyangiitis, microscopic polyangiitis or eosinophilic granulomatosis with polyangiitis. [2]

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