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The full clinical picture was first presented by Friedrich Wegener (1907–1990), a German pathologist, in two reports in 1936 and 1939, leading to the eponymous name Wegener's granulomatosis or Wegener granulomatosis (English: / ˈ v ɛ ɡ ə n ər /). [10]
Friedrich Wegener (7 April 1907, Varel – 9 July 1990, Lübeck, [veːɡɐnəɐ̯]) was a German pathologist who is notable for being a high-ranking Nazi physician and for his description of a rare disease originally referred to Wegener disease and now referred to as granulomatosis with polyangiitis. Although this disease was known before ...
Subsequent studies found that the cells infiltrating the midline tissues in cases of lethal midline granuloma that were not clearly diagnosed as granulomatosis with polyangiitis were: a) infected by the Epstein–Barr virus [2] and b) consisted of malignant lymphocytes, usually NK cells or, rarely, cytotoxic T cells. [3]
Prior to this it was known as Churg–Strauss syndrome, named after Jacob Churg and Lotte Strauss, who first published about the syndrome in 1951 using the term allergic granulomatosis to describe it. [3] It is a type of systemic necrotizing vasculitis. Effective treatment of EGPA requires suppression of the immune system with medication.
Granulomatosis with polyangiitis, formerly known as Wegener's granulomatosis, is a rare immune-mediated systemic disease with an unclear etiology. It manifests pathologically as an inflammatory response pattern in the kidneys, upper and lower respiratory tracts , and granulomatous inflammation, which includes necrosis .
A Wisconsin doctor ran seven marathons on seven continents, from Antarctica to North America, to raise awareness of testicular cancer after previously battling the disease.
First change: As per Dr. Lebovic and other ENT doctors that treat Wegener's Granulomatosis (in the WG discussion group) tracheotomy is not a good method for treating SS. First, the patient has dilation. Most surgery causes scar tissue to grow in the SS, making the problem worse for the patient.
During active cancer treatment, patients face many smaller battles on the path to remission. One of those lesser-known struggles is a condition known as chemo mouth, a painful side effect of ...