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  2. Action potential - Wikipedia

    en.wikipedia.org/wiki/Action_potential

    When an action potential arrives at the end of the pre-synaptic axon (top), it causes the release of neurotransmitter molecules that open ion channels in the post-synaptic neuron (bottom). The combined excitatory and inhibitory postsynaptic potentials of such inputs can begin a new action potential in the post-synaptic neuron.

  3. Neuron - Wikipedia

    en.wikipedia.org/wiki/Neuron

    A neuron, neurone, [1] or nerve ... the neuron generates an all-or-nothing electrochemical pulse called an action potential. This potential travels rapidly along the ...

  4. Chemical synapse - Wikipedia

    en.wikipedia.org/wiki/Chemical_synapse

    Artistic interpretation of the major elements in chemical synaptic transmission. An electrochemical wave called an action potential travels along the axon of a neuron.When the action potential reaches the presynaptic terminal, it provokes the release of a synaptic vesicle, secreting its quanta of neurotransmitter molecules.

  5. Membrane potential - Wikipedia

    en.wikipedia.org/wiki/Membrane_potential

    The ion pump most relevant to the action potential is the sodium–potassium pump, which transports three sodium ions out of the cell and two potassium ions in. [13] [14] As a consequence, the concentration of potassium ions K + inside the neuron is roughly 30-fold larger than the outside concentration, whereas the sodium concentration outside ...

  6. Excitatory postsynaptic potential - Wikipedia

    en.wikipedia.org/wiki/Excitatory_postsynaptic...

    In neuroscience, an excitatory postsynaptic potential (EPSP) is a postsynaptic potential that makes the postsynaptic neuron more likely to fire an action potential. This temporary depolarization of postsynaptic membrane potential, caused by the flow of positively charged ions into the postsynaptic cell, is a result of opening ligand-gated ion ...

  7. Hodgkin–Huxley model - Wikipedia

    en.wikipedia.org/wiki/Hodgkin–Huxley_model

    The electrochemical gradients driving the flow of ions are represented by batteries (E), and ion pumps and exchangers are represented by current sources (I p). The Hodgkin–Huxley model , or conductance-based model , is a mathematical model that describes how action potentials in neurons are initiated and propagated.

  8. Gating (electrophysiology) - Wikipedia

    en.wikipedia.org/wiki/Gating_(electrophysiology)

    Neurotransmitters are initially stored and synthesized in vesicles at the synapse of a neuron. When an action potential occurs in a cell, the electrical signal reaches the presynaptic terminal and the depolarization causes calcium channels to open, releasing calcium to travel down its electrochemical gradient.

  9. Dale's principle - Wikipedia

    en.wikipedia.org/wiki/Dale's_principle

    Illustration of the major elements in chemical synaptic transmission. An electrochemical wave called an action potential travels along the axon of a neuron.When the wave reaches a synapse, it provokes release of a puff of neurotransmitter molecules, which bind to chemical receptor molecules located in the membrane of another neuron, on the opposite side of the synapse.