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Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease, also known as pseudogout and pyrophosphate arthropathy, is a rheumatologic disease which is thought to be secondary to abnormal accumulation of calcium pyrophosphate dihydrate crystals within joint soft tissues. [1] The knee joint is most commonly affected. [2]
Other conditions that can look similar include CPPD (pseudogout), rheumatoid arthritis, psoriatic arthritis, palindromic rheumatism, and reactive arthritis. [1] [10] Gouty tophi, in particular when not located in a joint, can be mistaken for basal cell carcinoma [56] or other neoplasms. [57]
Crystal arthropathy is a class of joint disorder (called arthropathy) that is characterized by accumulation of tiny crystals in one or more joints. Polarizing microscopy and application of other crystallographic techniques have improved identification of different microcrystals including monosodium urate , calcium pyrophosphate dihydrate ...
Periods when gout symptoms are more severe are called gout flares or gout attacks. ... well, particularly those in the lower body. For example, gout in ankles or gout in knee joints may also occur ...
Chondrocalcinosis does not always lead to symptoms. However, chondrocalcinosis in the presence of CPPD may cause symptoms similar to Pseudogout, Pseudo-rheumatoid arthritis, and Pseudo-osteoarthritis. Chondrocalcinosis may be accompanied by joint pain, joint swelling, and decreased range of motion. [9] Chondrocalcinosis sites
Tophi form in the joints, cartilage, bones, and other places throughout the body. Sometimes, tophi break through the skin and appear as white or yellowish-white, chalky nodules. Without treatment, tophi may develop on average about ten years after the onset of gout, although their first appearance can range from three to forty-two years.
Milwaukee shoulder syndrome (MSS) (apatite-associated destructive arthritis/Basic calcium phosphate (BCP) crystal arthritis/rapid destructive arthritis of the shoulder) [1] is a rare [2] rheumatological condition similar to pseudogout, associated with periarticular or intra-articular deposition of hydroxyapatite or basic calcium phosphate (BCP) crystals.
Other joints such as sutures between the bones of the skull permit very little movement (only during birth) in order to protect the brain and the sense organs. [3] The connection between a tooth and the jawbone is also called a joint, and is described as a fibrous joint known as a gomphosis. Joints are classified both structurally and ...