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Artistic depiction of pseudogout crystals (calcium pyrophosphate dihydrate crystals) Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease, also known as pseudogout and pyrophosphate arthropathy, is a rheumatologic disease which is thought to be secondary to abnormal accumulation of calcium pyrophosphate dihydrate crystals within joint soft tissues. [1]
Other conditions that can look similar include CPPD (pseudogout), rheumatoid arthritis, psoriatic arthritis, palindromic rheumatism, and reactive arthritis. [1] [10] Gouty tophi, in particular when not located in a joint, can be mistaken for basal cell carcinoma [56] or other neoplasms. [57]
Crystal arthropathy is a class of joint disorder (called arthropathy) that is characterized by accumulation of tiny crystals in one or more joints. Polarizing microscopy and application of other crystallographic techniques have improved identification of different microcrystals including monosodium urate , calcium pyrophosphate dihydrate ...
Gout in foot joints is most common, with gout often affecting the big toe joint. However, other joints can be affected as well, particularly those in the lower body. For example, gout in ankles or ...
Tophi form in the joints, cartilage, bones, and other places throughout the body. Sometimes, tophi break through the skin and appear as white or yellowish-white, chalky nodules . Without treatment, tophi may develop on average about ten years after the onset of gout, although their first appearance can range from three to forty-two years.
The bones become fragile and deformed over time as a result. Orthopedic pathology, also known as bone pathology is a subspecialty of surgical pathology which deals with the diagnosis and feature of many bone diseases, specifically studying the cause and effects of disorders of the musculoskeletal system.
Chondrocalcinosis does not always lead to symptoms. However, chondrocalcinosis in the presence of CPPD may cause symptoms similar to Pseudogout, Pseudo-rheumatoid arthritis, and Pseudo-osteoarthritis. Chondrocalcinosis may be accompanied by joint pain, joint swelling, and decreased range of motion. [9] Chondrocalcinosis sites
Joints are classified both structurally and functionally. [4] Joints play a vital role in the human body, contributing to movement, stability, and overall function. They are essential for mobility and flexibility, connecting bones and facilitating a wide range of motions, from simple bending and stretching to complex actions like running and ...