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Databases for oncogenomic research are biological databases dedicated to cancer data and oncogenomic research. They can be a primary source of cancer data, offer a certain level of analysis (processed data) or even offer online data mining .
The focus is on innovative research in data mining, knowledge discovery, and large-scale data analytics. Papers emphasizing theoretical foundations are particularly encouraged, as are novel modeling and algorithmic approaches to specific data mining problems in scientific, business, medical, and engineering applications.
The Reproducibility Project: Cancer Biology showed that of 193 experiments from 53 top papers about cancer published between 2010 and 2012, only 50 experiments from 23 papers have authors who provided enough information for researchers to redo the studies, sometimes with modifications.
Clustering is central to much data-driven bioinformatics research and serves as a powerful computational method whereby means of hierarchical, centroid-based, distribution-based, density-based, and self-organizing maps classification, has long been studied and used in classical machine learning settings.
Pan-cancer studies aim to detect the genes whose mutation is conducive to oncogenesis, as well as recurrent genomic events or aberrations between different tumors.For these studies, it is necessary to standardize the data between multiple platforms, establishing criteria between different researchers to work on the data and present the results.
Semantic data mining is a subset of data mining that specifically seeks to incorporate domain knowledge, such as formal semantics, into the data mining process.Domain knowledge is the knowledge of the environment the data was processed in. Domain knowledge can have a positive influence on many aspects of data mining, such as filtering out redundant or inconsistent data during the preprocessing ...
The ways in which data mining can be used can in some cases and contexts raise questions regarding privacy, legality, and ethics. [28] In particular, data mining government or commercial data sets for national security or law enforcement purposes, such as in the Total Information Awareness Program or in ADVISE, has raised privacy concerns. [29 ...
Some of the problems tackled by CRI are: creation of data warehouses of health care data that can be used for research, support of data collection in clinical trials by the use of electronic data capture systems, streamlining ethical approvals and renewals (in US the responsible entity is the local institutional review board), maintenance of ...