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  2. Spironolactone - Wikipedia

    en.wikipedia.org/wiki/Spironolactone

    Spironolactone improves left ventricular diastolic function in patients with heart failure with preserved ejection fraction, however it has no effect on mortality and hospitalization. [43] [44] Due to its antiandrogenic properties, spironolactone can cause effects associated with low androgen levels and hypogonadism in males. For this reason ...

  3. Edema - Wikipedia

    en.wikipedia.org/wiki/Edema

    Treatment depends on the underlying cause. [2] If the underlying mechanism involves sodium retention, decreased salt intake and a diuretic may be used. [2] Elevating the legs and support stockings may be useful for edema of the legs. [3] Older people are more commonly affected. [3] The word is from the Ancient Greek οἴδημα oídēma ...

  4. Pharmacodynamics of spironolactone - Wikipedia

    en.wikipedia.org/wiki/Pharmacodynamics_of...

    Spironolactone has been identified as an inhibitor of NRG1‐ERBB4 signaling. [142] Spironolactone has been found to act as a potent inhibitor of the pannexin 1 channel, and this action appears to be involved in its antihypertensive effects independently of MR antagonism. [143] Spironolactone has been found to block hERG channels. [144]

  5. Everything I Wish I Knew About Taking Spironolactone for Acne

    www.aol.com/news/everything-know-taking...

    Spironolactone is an acne treatment prescribed by dermatologists. Find out how spironolactone improves the appearance of hormonal acne, side effects, and more. Everything I Wish I Knew About ...

  6. While sweating is normal, excessive sweating may have deeper underlying causes. But there are ways to manage the condition to make sure that you can still live your best life. This story was ...

  7. Hyperandrogenism - Wikipedia

    en.wikipedia.org/wiki/Hyperandrogenism

    Administration of high-dose testosterone in men over a course of weeks can cause an increase in aggression and hypomanic symptoms, though these were seen in only a minority of subjects. [15] Acute high-dose anabolic-androgenic steroid administration in males attenuates endogenous sex hormone production and affects the thyroid hormone axis .

  8. What does a heat rash look like? How to identify and treat it

    www.aol.com/news/does-heat-rash-look-identify...

    Heat rashes are a common summer skin problem caused by excessive sweating to the point that the sweat gets trapped under the skin. Adults most often develop heat rashes on parts of the body where ...

  9. Cushing's syndrome - Wikipedia

    en.wikipedia.org/wiki/Cushing's_syndrome

    Cushing's syndrome is a collection of signs and symptoms due to prolonged exposure to glucocorticoids such as cortisol. [4] [9] [10] Signs and symptoms may include high blood pressure, abdominal obesity but with thin arms and legs, reddish stretch marks, a round red face due to facial plethora, [11] a fat lump between the shoulders, weak muscles, weak bones, acne, and fragile skin that heals ...