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[10] [11] [12] Long-term use of certain substituted amphetamines, particularly methamphetamine, can reduce dopamine activity in the brain. [13] [4] Adderall- Prescribed Amphetamine. For amphetamine dependent individuals, psychotherapy is currently the best treatment option as no pharmacological treatment has been approved. [8]
In an Australian study of 309 active methamphetamine users, 18% had experienced a clinical level psychosis in the past year. [9] Commonly abused amphetamines include methamphetamine , MDMA , 4-FA , as well as substituted cathinones like α-PVP , MDPV , and mephedrone , though a large number of other closely related compounds have been recently ...
Substance-induced psychosis (commonly known as toxic psychosis or drug-induced psychosis) is a form of psychosis that is attributed to substance intoxication, withdrawal or recent consumption of psychoactive drugs. It is a psychosis that results from the effects of various substances, such as medicinal and nonmedicinal substances, legal and ...
Methamphetamine fatality from ATS have been reported after ingestion of a minimal dose of 1.3 mg/kg, while the estimated minimum lethal dose in a non-addicted adult is 200 mg. [14] [26] Generally, children are more likely to develop toxicity and have lower chances of developing tolerance.
In low doses, methamphetamine can cause an elevated mood and increase alertness, concentration, and energy in fatigued individuals. [94] [139] At higher doses, it can induce psychosis, rhabdomyolysis, and cerebral hemorrhage. [94] [139] Methamphetamine is known to have a high potential for abuse and addiction.
Adrenergic storms are usually caused by overdoses of stimulants, especially cocaine or methamphetamine, or eating foods high in tyramine while taking monoamine oxidase inhibitors. [9] A subarachnoid hemorrhage can also cause an adrenergic storm. [9]
Methamphetamine was discovered in 1893 and exists as two enantiomers: levo-methamphetamine and dextro-methamphetamine. [ note 2 ] Methamphetamine properly refers to a specific chemical substance, the racemic free base , which is an equal mixture of levomethamphetamine and dextromethamphetamine in their pure amine forms, but the hydrochloride ...
Biological Toxins such as Diphtheria toxin [18]; Radiation Therapy is known to cause radiation-induced heart disease (RIHD) [19] These agents can lead to varying degrees of cardiotoxicity, and their effects may be dose-dependent and influenced by individual factors such as pre-existing cardiovascular disease and genetic predispositions that can foster greater sensitivity to any cardiac damage.