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Fexofenadine, sold under the brand name Allegra among others, [10] is an antihistamine pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever and urticaria. [ 11 ] Therapeutically, fexofenadine is a selective peripheral H 1 blocker .
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Older people are more likely to experience drowsiness from antihistamine use than younger people. [1] Continuous and/or cumulative use of anticholinergic medications, including first-generation antihistamines, is associated with higher risk for cognitive decline and dementia in older people.
The elimination half-life of cetirizine ranges from 6.5 to 10 hours in healthy adults, with a mean across studies of approximately 8.3 hours. [ 3 ] [ 2 ] The elimination half-life of cetirizine is increased in the elderly (to 12 hours), in hepatic impairment (to 14 hours), and in renal impairment (to 20 hours). [ 2 ]
“A lot of people will avoid getting an evaluation because of common misconceptions that these memory changes are normal with increasing age, but that’s not a helpful assumption,” Kaiser says.
Nose breathing is, loosely speaking, a self-care practice that has long been embraced by woo-woo spiritual seekers in meditation and by performance athletes for increased endurance.