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House construction site using AAC (Ytong) blocks in Ablis, France. Residential house constructed of AAC (Siporex) blocks in Kuopio, Finland. AAC was first created in the mid-1920s by the Swedish architect and inventor Dr. Johan Axel Eriksson (1888–1961), [11] [12] along with Professor Henrik Kreüger at the Royal Institute of Technology.
Firsocostat (formerly GS-976, ND-630, NDI-010976) is a potent allosteric ACC inhibitor, acting at the BC domain of ACC. [29] Firsocostat is under development in 2019 (Phase II) [ 30 ] by the pharmaceutical company Gilead as part of a combination treatment for non-alcoholic steatohepatitis (NASH), believed to be an increasing cause of liver failure.
The reaction catalyzed by 1-aminocyclopropane-1-carboxylic acid synthase (ACS) is the committed and rate-limiting step in the biosynthesis of ethylene [20], a gaseous plant hormone that is responsible for the initiation of fruit ripening, shoot and root growth and differentiation, leaf and fruit abscission, flower opening, and flower and leaf ...
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