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Adverse drug reaction: palmoplantar erythrodysesthesia (acral erythema) Because circulating levels of estrogen increase in both cirrhosis and pregnancy, estrogen was thought to be the main cause for the increased vascularity. More recently, nitric oxide has also been implicated in the pathogenesis of palmar erythema. [5]
Chemotherapy-induced acral erythema, also known as palmar-plantar erythrodysesthesia or hand-foot syndrome is reddening, swelling, numbness and desquamation (skin sloughing or peeling) on palms of the hands and soles of the feet (and, occasionally, on the knees, elbows, and elsewhere) that can occur after chemotherapy in patients with cancer.
The first reported case was in 1878 by Silas Weir Mitchell who suggested the term erythromelalgia to describe a syndrome of red congestion and burning pain in the hands and feet. [49] [50] Silas Weir Mitchell. He distinguished it from the painful red limbs seen in some patients with gout or rheumatoid arthritis. [49]
Erythema marginatum (also known as chicken wire erythema) [1] is an acquired skin condition which primarily affects the arms, trunk, and legs. [2] It is a type of erythema (redness of the skin or mucous membranes) characterised by bright pink or red circular lesions which have sharply-defined borders and faint central clearing.
Traditionally, necrolytic acral erythema manifests as distinct, dark red hyperkeratotic plaques with a keratotic border that are usually found on the dorsum of the foot and toes. Ankles, legs, and knees may also be affected in some cases. [4] On occasion, lesions may appear on the buttocks, genitalia, hands, and elbows.
Erythema (Ancient Greek: ἐρύθημα, from Greek erythros 'red') is redness of the skin or mucous membranes, caused by hyperemia (increased blood flow) in superficial capillaries. [1] It occurs with any skin injury, infection, or inflammation. Examples of erythema not associated with pathology include nervous blushes. [2]
Red eyes. Burning eyes. Itchy eyes. Painful eyes. Watery eyes. Puffy eyelids. Blurry or hazy vision. Sensitivity to light. Mucus, pus or thick yellow discharge from the eye. ... Palms of hands ...
Janeway lesions present as red, painless macules and papules on the palms and soles. [2]They are not common and are frequently indistinguishable from Osler's nodes.Rarely, they have been reported in cases of systemic lupus erythematosis (SLE), gonococcemia (disseminated gonorrhoea), haemolytic anaemia and typhoid fever.