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Ketamine-assisted psychotherapy (KAP) is the use of prescribed doses of ketamine as an adjunct to psychotherapy sessions. KAP shows significant potential in treating mental disorders such as treatment-resistant depression (TRD), anxiety, obsessive–compulsive disorders (OCD), post-traumatic stress disorders (PTSD), and other conditions. [1]
Esketamine, sold under the brand names Spravato (for depression) and Ketanest (for anesthesia) among others, [10] [12] is the S(+) enantiomer of ketamine. [5] [13] It is a dissociative hallucinogen drug used as a general anesthetic and as an antidepressant for treatment of depression.
Sometimes, healthcare professionals prescribe alpha-blockers off-label to help with PTSD symptoms, especially recurring nightmares. ... Ketamine Therapy. While researchers aren’t entirely sure ...
Though ketamine itself is not approved as a treatment for any psychiatric condition, ketamine clinics have opened up across the United States to provide this treatment off-label. Typically, these ...
It's also crucial that ketamine therapy is given within a medically supervised setting, since ketamine’s psychedelic properties cause temporary sensory alteration. Dr. Green adds, “People who ...
Here, we explore ketamine therapy’s safety with Steven L. Mandel, M.D., co-founder of Ketamine Clinics Los Angeles and the founder of the nonprofit American Society of Ketamine Physicians ...
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The S-(+) and R-(–) stereoisomers of ketamine bind to the dizocilpine site of the NMDA receptor with different affinities, the former showing approximately 3- to 4-fold greater affinity for the receptor than the latter. As a result, the S isomer is a more potent anesthetic and analgesic than its R counterpart. [118]
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