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  2. Analgesic nephropathy - Wikipedia

    en.wikipedia.org/wiki/Analgesic_nephropathy

    A small proportion of individuals with analgesic nephropathy may develop end-stage kidney disease. Analgesic nephropathy was once a common cause of kidney injury and end-stage kidney disease in parts of Europe, Australia, and the United States. In most areas, its incidence has declined sharply since the use of phenacetin fell in the 1970s and ...

  3. Phenacetin - Wikipedia

    en.wikipedia.org/wiki/Phenacetin

    One notable death that can possibly be attributed to the use of this drug was that of the aviation pioneer Howard Hughes. He had been using phenacetin extensively for the treatment of chronic pain; it was stated during his autopsy that phenacetin use may have been the cause of his kidney failure. [18]

  4. Bex (compound analgesic) - Wikipedia

    en.wikipedia.org/wiki/Bex_(compound_analgesic)

    However, it became recognised that these medications were addictive, and Priscilla Kincaid-Smith found that the large doses of phenacetin ingested by habitual users were responsible for widespread kidney disease. [4] [5] The phenacetin was removed from Bex in 1975. [6] Bex has also been linked to kidney cancer. [7]

  5. Kidney disease - Wikipedia

    en.wikipedia.org/wiki/Kidney_disease

    Kidney disease usually causes a loss of kidney function to some degree and can result in kidney failure, the complete loss of kidney function. Kidney failure is known as the end-stage of kidney disease, where dialysis or a kidney transplant is the only treatment option.

  6. 3 biggest health hazards threaten all Americans, says oncologist

    www.aol.com/3-biggest-health-hazards-threaten...

    "I think the No. 1 problem in America is the chronic disease of obesity," Prato said, largely due to "insulin receptor sensitivity issues," which is when the body’s cells become less responsive ...

  7. Nephrotoxicity - Wikipedia

    en.wikipedia.org/wiki/Nephrotoxicity

    Drug-induced glomerular disease is not common but there are a few drugs that have been implicated. Glomerular lesions occur primarily through immune-mediated pathways rather than through direct drug toxicity. Heroin and Pamidronate are known to cause focal segmental glomerulosclerosis; Gold salts therapy can cause membranous nephropathy [4 ...