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From C4–5, the thyroid cartilage [10] From C6–7, the cricoid cartilage [10] At C6, the oesophagus becomes continuous with the laryngopharynx and also where the larynx becomes continuous with the trachea. It is also the level where the carotid pulse can be palpated against the transverse process of the C6 vertebrae.
Transcription factor Sp7, also called Osterix (Osx), is a protein that in humans is encoded by the SP7 gene. [5] It is a member of the Sp family of zinc-finger transcription factors [5] It is highly conserved among bone-forming vertebrate species [6] [7] It plays a major role, along with Runx2 and Dlx5 in driving the differentiation of mesenchymal precursor cells into osteoblasts and ...
The target of C5 convertase is complement protein C5. C5 is a two-chain (α, β) plasma glycoprotein (Mr = 196,000). C5 and C3 have similar structure. However, C5 does not appear to contain the internal thiol ester group reported for C3 and C4. C5 has relatively few disulfide bonds.
C5 convertase then cleaves C5 into C5a and C5b. [3] Like C3a, C5a is also an anaphylatoxin that interacts with its cognate C5a receptor (C5aR) to attract leukocytes. [ 1 ] Subsequent interactions between C5b and other terminal components C6, C7, C8, and C9 form the membrane attack complex or the C5b-9 complex which forms pores on the target ...
The thyroid cartilage is found between the levels of the C4 to C5 vertebrae. The oblique line is a line on the thyroid cartilage. It marks the upper lateral borders of the thyroid gland. Two muscles originate along the line, the thyrohyoid muscle and theinferior pharyngeal constrictor. The sternothyroid inserts along the line. Thyroid cartilage
Chondrosarcoma is a bone sarcoma, a primary cancer composed of cells derived from transformed cells that produce cartilage. [1] A chondrosarcoma is a member of a category of tumors of bone and soft tissue known as sarcomas. About 30% of bone sarcomas are chondrosarcomas. [2] It is resistant to chemotherapy and radiotherapy. Unlike other primary ...
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