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Leprosy has historically been associated with social stigma, which continues to be a barrier to self-reporting and early treatment. [4] Leprosy is classified as a neglected tropical disease. [21] World Leprosy Day was started in 1954 to draw awareness to those affected by leprosy. [22] [4] The study of leprosy and its treatment is known as ...
A leprostatic agent is a drug that interferes with proliferation of the bacterium that causes leprosy. [1] [2] The following agents are leprostatic agents: [3] acedapsone; clofazimine; dapsone; desoxyfructo-serotonin; diucifon; ethionamide; rifampicin; rifapentine; sulfameter; thalidomide; Leprosy is a chronic infectious disease caused by ...
Mycobacterium leprae, the causative agent of leprosy, was discovered by G. H. Armauer Hansen in Norway in 1873, making it the first bacterium to be identified as causing disease in humans. [2] [25] Hansen observed a number of nonrefractile small rods in unstained tissue sections. The rods were not soluble in potassium lye, and they were acid ...
Leishmaniasis is a wide array of clinical manifestations caused by protozoal parasites of the Trypanosomatida genus Leishmania. [7] It is generally spread through the bite of phlebotomine sandflies, Phlebotomus and Lutzomyia, and occurs most frequently in the tropics and sub-tropics of Africa, Asia, the Americas, and southern Europe.
Hansen remained medical officer for leprosy in Norway and it was through his efforts that the leprosy acts of 1877 and 1885 were passed, leading to a steady decline of the disease in Norway from 1,800 known cases in 1875 to just 575 cases in 1901. Hansen had had syphilis since the 1860s but died of heart disease. He was an atheist. [10] [11]
The American Mission also built asylums for leprosy patients, but these were eventually closed or converted into hospitals following the discovery of a cure in 1948. [4] In 1968, the German Leprosy Relief Association-backed organization Aid to Leprosy Patients assumed control of the hospital, and by 1965, it began serving as a referral center. [4]
Mycobacterium lepromatosis can induce diffuse lepromatous leprosy (DLL), typically known to occur in Mexico and the Caribbean. [5] [6] DLL is a severe form of leprosy which manifests through nerve invasion and extensive skin ulcerations due to massive AFB burden in internal organs. [5]
The Leprosy Notes of 1928 and 1929 as well as all Leprosy Review issues from 1930 to 2001 are freely available online thanks to the Full Text Leprosy Project, an initiative of the Lauro de Souza Lima Institute of Secretary of Health of São Paulo, in cooperation with the Latin American and Caribbean Center on Health Sciences Information and The ...