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Mammillary bodies, and their projections to the anterior thalamus via the mammillothalamic tract, are important for recollective memory. [7] According to studies of rats with mammillary body lesions, damage to the medial mammillary nucleus lead to spatial memory deficits.
The mammillary bodies directly or indirectly connect to the amygdala, hippocampus, and thalami as major structures in the limbic system. [6] The mammillothalamic tract carries signals from the mammillary bodies via the anterior thalamus to support spatial memory .
The mammillotegmental fasciculus (mammillotegmental tract, or mammillotegmental bundle of Gudden) is a small bundle of efferent fibers from the hypothalamus running from the mammillary body to the tegmentum. [1] Its functions are not well defined for humans, but based on animal studies it seems to be related to regulating visceral function and ...
The hypothalamus is divided into four regions (preoptic, supraoptic, tuberal, mammillary) in a parasagittal plane, indicating location anterior-posterior; and three zones (periventricular, intermediate, lateral) in the coronal plane, indicating location medial-lateral. [7] Hypothalamic nuclei are located within these specific regions and zones. [8]
Its various components support a variety of functions including emotion, behavior, long-term memory, and olfaction. [2] The limbic system is involved in lower order emotional processing of input from sensory systems and consists of the amygdala, mammillary bodies, stria medullaris, central gray and dorsal and ventral nuclei of Gudden. [3]
The anterior nuclei receive afferents from the hippocampus and subiculum directly via the fornix, and indirectly via the mammillary bodies and mammillothalamic tract (MTT). They send efferent fibers to the cingulate gyrus, limbic, and orbitofrontal cortex. [1] The anterior nuclei of the thalamus display functions pertaining to memory.
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The tuber cinereum is a convex mass of grey matter, [3]: 495 a ventral/inferior distention of the hypothalamus forming the floor of the third ventricle. [citation needed] The portion of the tuber cinerum at the base of the infundibulum (pituitary stalk) is the median eminence; [2] the infundibulum extends ventrally/inferiorly from the median eminence to become continuous with the infundibulum.