Search results
Results From The WOW.Com Content Network
Scleroderma is a group of autoimmune diseases that may result in changes to the skin, blood vessels, muscles, and internal organs. [ 2 ] [ 6 ] [ 8 ] The disease can be either localized to the skin or involve other organs, as well. [ 2 ]
Morphea is a form of scleroderma that is more common in women than men, in a ratio 3:1. [17] Morphea occurs in childhood as well as in adult life. [ 3 ] Morphea is an uncommon condition that is thought to affect 2 to 4 in 100,000 people. [ 18 ]
Systemic scleroderma, or systemic sclerosis, is an autoimmune rheumatic disease characterised by excessive production and accumulation of collagen, called fibrosis, in the skin and internal organs and by injuries to small arteries. There are two major subgroups of systemic sclerosis based on the extent of skin involvement: limited and diffuse ...
Sclerodactyly is often preceded by months or even years by Raynaud's phenomenon when it is part of systemic scleroderma. [citation needed] The term "sclerodactyly" comes from Greek skleros 'hard' and daktylos 'digit'. It is generally associated with systemic scleroderma and mixed connective tissue disease, and auto-immune disorders.
It is a feature of many craniofacial syndromes, including Freeman–Sheldon syndrome and Sheldon-Hall syndromes (or distal arthrogryposis multiplex congenita).It may present with whistling-face feature, as well, as in Freeman-Sheldon syndrome.
Telangiectasias, aside from presenting in many other conditions, are one of the features of the acronymically named CREST syndrome, a form of systemic scleroderma. The syndrome recognises the significantly co-presenting symptoms of calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly and telangiectasia.
CREST syndrome, also known as the limited cutaneous form of systemic sclerosis (lcSSc), is a multisystem connective tissue disorder.The acronym "CREST" refers to the five main features: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.
Oral submucous fibrosis (OSF) is a chronic, complex, premalignant (1% transformation risk) condition of the oral cavity, characterized by juxta-epithelial inflammatory reaction and progressive fibrosis of the submucosal tissues (the lamina propria and deeper connective tissues).