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Scleroderma is a group of autoimmune diseases that may result in changes to the skin, blood vessels, muscles, and internal organs. [ 2 ] [ 6 ] [ 8 ] The disease can be either localized to the skin or involve other organs, as well. [ 2 ]
Morphea is a form of scleroderma that mainly involves isolated patches of hardened skin on the face, hands, and feet, or anywhere else on the body, usually with no internal organ involvement. [1] However, in Deep Morphea inflammation and sclerosis can be found in the deep dermis, panniculus, fascia, superficial muscle and bone. [2]: 130
Systemic scleroderma, or systemic sclerosis, is an autoimmune rheumatic disease characterised by excessive production and accumulation of collagen, called fibrosis, in the skin and internal organs and by injuries to small arteries. There are two major subgroups of systemic sclerosis based on the extent of skin involvement: limited and diffuse ...
Parry–Romberg syndrome (PRS) is a rare disease presenting in early childhood [1] characterized by progressive shrinkage and degeneration of the tissues beneath the skin, usually on only one side of the face (hemifacial atrophy) but occasionally extending to other parts of the body. [2]
Scleroderma. This disorder causes tissue thickening and hardening due to excess collagen production. It can affect the skin, tissues, blood vessels, and sometimes internal organs.
Treatment of sclerodactyly is by physical therapy, phototherapy, surgery, topical corticosteroids or vitamin D analogues, and systemic immunosuppressive drugs when the condition is part of systemic scleroderma [citation needed]. Localized treatment won't halt systemic disease, but can restore function and cosmetic aspects of the affected digits.
The coalescence of papules on the face, particularly on the glabella, results in longitudinal folding and gives the appearance of a leonine facies. In scleromyxedema, symptoms can occur on larger part of the body. Redness and scleroderma-like induration occurs on the skin. In addition, the mobility of the lips, hands, arms, and legs is reduced.
Beka Setzer, an Ohio mother of two young daughters, took to Facebook last summer to share shocking photos of her daughter Emmalee's legs after a day spent playing outside went awry. "PSA," she wrote.