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Vitamin B 12 is the most chemically complex of all vitamins, [6] and for humans the only vitamin that must be sourced from animal-derived foods or supplements. [2] [7] Only some archaea and bacteria can synthesize vitamin B 12. [8] Vitamin B 12 deficiency is a widespread condition that is particularly prevalent in populations with low ...
Dietary supplements containing all eight are referred to as a vitamin B complex. Individual B vitamins are referred to by B-number or by chemical name, such as B 1 for thiamine, B 2 for riboflavin, and B 3 for niacin, [1] [2] while some are more commonly recognized by name than by number, such as pantothenic acid (B 5), biotin (B 7), and folate ...
6% (< 60 years old), 20% (> 60 years old) [4] Vitamin B12 deficiency, also known as cobalamin deficiency, is the medical condition in which the blood and tissue have a lower than normal level of vitamin B 12. [5] Symptoms can vary from none to severe. [1] Mild deficiency may have few or absent symptoms. [1]
“Like vitamin C, B-complex vitamins are water-soluble. As a result, they cannot be stored for later use. The body will use what it needs, and the rest is excreted as waste in the urine.” ...
Frequency. 1 per 1000 people [8] Pernicious anemia is a disease where not enough red blood cells are produced due to a deficiency of vitamin B 12. [5] Those affected often have a gradual onset. [5] The most common initial symptoms are feeling tired and weak. [4]
The structure of vitamin B 12 was the first low-molecular weight natural product determined by x-ray analysis rather than by chemical degradation. Thus, while the structure of this novel type of complex biomolecule was established, its chemistry remained essentially unknown; exploration of this chemistry became one of the tasks of the vitamin's chemical synthesis.
Methylcobalamin (mecobalamin, MeCbl, or MeB 12) is a cobalamin, a form of vitamin B 12. It differs from cyanocobalamin in that the cyano group at the cobalt is replaced with a methyl group. [1] Methylcobalamin features an octahedral cobalt (III) centre and can be obtained as bright red crystals. [2] From the perspective of coordination ...
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