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Macrocytosis isn't a specific disease, but it may indicate an underlying problem that requires medical evaluation. Common causes of macrocytosis include: Vitamin B-12 deficiency. Folate deficiency. Liver disease. Alcoholism. Hypothyroidism. A side effect of certain medications, such as those used to treat cancer, seizures and autoimmune disorders.
Too many mast cells can build up in the skin, liver, spleen, bone marrow or intestines. Less commonly, other organs such as the brain, heart or lungs also may be affected. Signs and symptoms of systemic mastocytosis may include: Flushing, itching or hives. Abdominal pain, diarrhea, nausea or vomiting. Anemia or bleeding disorders.
Diagnosis. To diagnose systemic mastocytosis, your doctor will likely start by reviewing your symptoms and discussing your medical history, including medications you've taken. He or she can then order tests that look for high levels of mast cells or the substances they release. Evaluation of organs affected by the condition also may be done.
Anemia is a problem of not having enough healthy red blood cells or hemoglobin to carry oxygen to the body's tissues. Hemoglobin is a protein found in red cells that carries oxygen from the lungs to all other organs in the body. Having anemia can cause tiredness, weakness and shortness of breath. There are many forms of anemia.
You can take steps to help yourself feel better if you've been diagnosed with polycythemia vera. Try to: Exercise. Moderate exercise, such as walking, can improve your blood flow. This helps decrease your risk of blood clots. Leg and ankle stretches and exercises also can improve your blood circulation. Avoid tobacco.
Polycythemia vera (pol-e-sy-THEE-me-uh VEER-uh) is a type of blood cancer. It causes your bone marrow to make too many red blood cells. These excess cells thicken your blood, slowing its flow, which may cause serious problems, such as blood clots. Polycythemia vera is rare. It usually develops slowly, and you might have it for years without ...
As the name implies, iron deficiency anemia is due to insufficient iron. Without enough iron, your body can't produce enough of a substance in red blood cells that enables them to carry oxygen (hemoglobin). As a result, iron deficiency anemia may leave you tired and short of breath. You can usually correct iron deficiency anemia with iron ...
Symptoms. Vitamin deficiency anemia usually develops slowly over several months to years. Signs and symptoms may be subtle at first but usually increase as the deficiency worsens. These may include: Fatigue. Shortness of breath. Dizziness. Pale or yellowish skin. Irregular heartbeats.
Rarely, in some kidney cancers or after kidney transplant, the kidneys might produce too much of the hormone erythropoietin. This causes the body to make more red blood cells. Red blood cell counts also can be high in nonalcoholic fatty liver disease. Nonalcoholic fatty liver disease. Causes shown here are commonly associated with this symptom.
Possible causes of high blood protein include: Amyloidosis. Dehydration. Hepatitis B. Hepatitis C. HIV/AIDS. Monoclonal gammopathy of undetermined significance (MGUS) Multiple myeloma. A high-protein diet doesn't cause high blood protein.