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The design of experiments (DOE), [1] also known as experiment design or experimental design, is the design of any task that aims to describe and explain the variation of information under conditions that are hypothesized to reflect the variation.
There are several methods of finding an optimal design, given an a priori restriction on the number of experimental runs or replications. Some of these methods are discussed by Atkinson, Donev and Tobias and in the paper by Hardin and Sloane. Of course, fixing the number of experimental runs a priori would be impractical. Prudent statisticians ...
Blocking: A schedule for conducting treatment combinations in an experimental study such that any effects on the experimental results due to a known change in raw materials, operators, machines, etc., become concentrated in the levels of the blocking variable. Note: the reason for blocking is to isolate a systematic effect and prevent it from ...
Bayesian experimental design provides a general probability-theoretical framework from which other theories on experimental design can be derived. It is based on Bayesian inference to interpret the observations/data acquired during the experiment. This allows accounting for both any prior knowledge on the parameters to be determined as well as ...
Plackett–Burman designs are experimental designs presented in 1946 by Robin L. Plackett and J. P. Burman while working in the British Ministry of Supply. [1] Their goal was to find experimental designs for investigating the dependence of some measured quantity on a number of independent variables (factors), each taking L levels, in such a way as to minimize the variance of the estimates of ...
In statistics, Box–Behnken designs are experimental designs for response surface methodology, devised by George E. P. Box and Donald Behnken in 1960, to achieve the following goals: Each factor, or independent variable, is placed at one of three equally spaced values, usually coded as −1, 0, +1.
Designed experiments with full factorial design (left), response surface with second-degree polynomial (right) In statistics, a factorial experiment (also known as full factorial experiment) investigates how multiple factors influence a specific outcome, called the response variable.
The Design of Experiments is a 1935 book by the English statistician Ronald Fisher about the design of experiments and is considered a foundational work in experimental design. [ 1 ] [ 2 ] [ 3 ] Among other contributions, the book introduced the concept of the null hypothesis in the context of the lady tasting tea experiment. [ 4 ]