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Micrograph showing a goblet cell carcinoid. H&E stain . The goblet cell carcinoid ( GCC ) is a rare biphasic gastrointestinal tract tumour that consists of a neuroendocrine component and a conventional carcinoma , histologically arising from Paneth cells .
Most hyperplastic polyps are found in the distal colon and rectum. [2] They have no malignant potential, [2] which means that they are no more likely than normal tissue to eventually become a cancer. [citation needed] Hyperplastic polyps on the right side of the colon do exhibit a malignant potential.
The colorectal adenoma is a benign glandular tumor of the colon and the rectum. It is a precursor lesion of the colorectal adenocarcinoma ( colon cancer ). [ 1 ] [ 2 ] [ 3 ] They often manifest as colorectal polyps .
Goblet cell-rich type: Elongated, fat crypts and little to no serration. Filled with goblet cells, extending to surface, which commonly has a tufted appearance. [11] Tubular adenoma: 2% at 1.5 cm [12] Low to high grade dysplasia [13] Over 75% of volume has tubular appearance. [14] Tubulovillous adenoma: 20% to 25% [15] 25–75% villous [14 ...
poorly differentiated (high grade) neuroendocrine carcinomas, which are the large cell neuroendocrine and small cell carcinomas. Additionally, the WHO scheme recognizes mixed tumors with both neuroendocrine and epithelial carcinoma features, such as goblet cell cancer, a rare gastrointestinal tract tumor. [6]
The signs and symptoms of colorectal cancer depend on the location of the tumor in the bowel, and whether it has spread elsewhere in the body ().The classic warning signs include: worsening constipation, blood in the stool, decrease in stool caliber (thickness), loss of appetite, loss of weight, and nausea or vomiting in someone over 50 years old. [15]
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