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  2. Cialis Side Effects: What to Expect (& How to Avoid Them) - AOL

    www.aol.com/cialis-side-effects-expect-avoid...

    As mentioned, Cialis can interact with other PDE5 inhibitors for ED, as well as medications prescribed to treat hypertension (high blood pressure), fungal infections, heart disease, heart failure ...

  3. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    Sildenafil and tadalafil are also indicated for the treatment of some subtypes of pulmonary hypertension, while tadalafil is also licensed for the treatment of benign prostatic hyperplasia. [1] PDE5 inhibitors have been used as a second line therapy in severe cases of Raynaud phenomenon when it is related to systemic sclerosis per The European ...

  4. Does Adderall Make You Last Longer in Bed or the Opposite? - AOL

    www.aol.com/does-adderall-last-longer-bed...

    If you have dysfunction problems like ED, prescription medication may be a good option to increase stamina. PDE5 inhibitors are ED drugs that can help you get aroused by increasing blood flow to ...

  5. Tadalafil: Your Ultimate Guide to Dosages, Side Effects & More

    www.aol.com/tadalafil-ultimate-guide-dosages...

    This guide to PDE5 inhibitors has more information about how tadalafil, sildenafil and other medications for ED work. There are a number of common use cases for this medication, including:

  6. Dutasteride - Wikipedia

    en.wikipedia.org/wiki/Dutasteride

    Dutasteride is used for treating BPH, colloquially known as an "enlarged prostate". [ 9 ] [ 14 ] It is approved by the Food and Drug Administration (FDA) in the U.S. for this indication. [ 15 ] A 2010 Cochrane review found a 25–26% reduction in the risk of developing prostate cancer with 5α-reductase inhibitor chemoprevention .

  7. Phosphodiesterase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Phosphodiesterase_inhibitor

    A phosphodiesterase inhibitor is a drug that blocks one or more of the five subtypes of the enzyme phosphodiesterase (PDE), thereby preventing the inactivation of the intracellular second messengers, cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) by the respective PDE subtype(s). The ubiquitous presence of this ...

  8. Is It Safe to Take Cialis Daily? - AOL

    www.aol.com/safe-cialis-daily-115900442.html

    Like other ED medications, Cialis is a PDE5 inhibitor. It works by blocking the effects of PDE5, or cGMP-specific phosphodiesterase type 5 — an enzyme that’s responsible for controlling the ...

  9. cGMP-specific phosphodiesterase type 5 - Wikipedia

    en.wikipedia.org/wiki/CGMP-specific_phosphodi...

    PDE5 inhibitor drugs are effective in men regardless of why they have erectile dysfunction — including vascular disease, nerve problems, and even psychological causes. [citation needed] PDE5-inhibiting drugs can cause a number of side-effects, including headache, lightheadedness, dizziness, flushing, nasal congestion, and changes in vision.