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Hypercholesterolemia, also called high cholesterol, is the presence of high levels of cholesterol in the blood. [1] It is a form of hyperlipidemia (high levels of lipids in the blood), hyperlipoproteinemia (high levels of lipoproteins in the blood), and dyslipidemia (any abnormalities of lipid and lipoprotein levels in the blood). [1]
Ninety-five million American adults, or about two in five, live with high cholesterol. Here's everything you need to know to treat and prevent it.
LDL cholesterol is the “bad” cholesterol that can increase the risk of heart disease and stroke when levels are too high. HDL cholesterol is “good” cholesterol and high levels of it can ...
The poll shows that, clearly, many people don’t know about the negative impact LDL cholesterol can have on heart health—a major concern since cardiovascular disease is the number one cause of ...
LDL cholesterol is produced naturally by the body, but eating a diet high in saturated fat, trans fats, and cholesterol can increase LDL levels. [43] Elevated LDL levels are associated with diabetes, hypertension, hypertriglyceridemia, and atherosclerosis. In a fasting lipid panel, a LDL greater than 160 mg/dL is abnormal. [37] [39]
In addition to plaque formation, LDL-C molecules can undergo oxidation. [1] Oxidation can cause further accumulation of cholesterol and the release of inflammatory cytokines, which damages the blood vessels. [1] [7] Due to the damaging effects of LDL-C, high levels increase the risk for cardiovascular disease and indicate dyslipidemia. [1]
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