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The source for the data below is the OECD Health Statistics 2018, released by the OECD in June 2018 and updated on 8 November 2018. [1]The unit of measurement used by the OECD is defined daily dose (DDD), defined as "the assumed average maintenance dose per day for a drug used on its main indication in adults". [2]
The World Health Organization Composite International Diagnostic Interview (CIDI) is a structured interview for psychiatric disorders.As the interview is designed for epidemiological studies, it can be administered by those who are not clinically trained and can be completed in a short amount of time.
Noradrenergic and specific serotonergic antidepressants (NaSSAs) are a class of psychiatric drugs used primarily as antidepressants. [1] They act by antagonizing the α 2 -adrenergic receptor and certain serotonin receptors such as 5-HT 2A and 5-HT 2C , [ 1 ] but also 5-HT 3 , [ 1 ] 5-HT 6 , and/or 5-HT 7 in some cases.
Serotonin antagonist and reuptake inhibitors (SARIs) are a class of drugs used mainly as antidepressants, but also as anxiolytics and hypnotics. They act by antagonizing serotonin receptors such as 5-HT 2A and inhibiting the reuptake of serotonin, norepinephrine, and/or dopamine. Additionally, most also antagonize α 1-adrenergic receptors.
This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification.
The Montgomery–Åsberg Depression Rating Scale (MADRS) is a ten-item [1] diagnostic questionnaire which mental health professionals use to measure the severity of depressive episodes in patients with mood disorders.
The Center for Epidemiologic Studies Depression Scale for Children (CES-DC) is a modified version of the Center for Epidemiologic Studies Depression Scale. This measure assesses both depressive symptoms as well as symptom improvement in a wide range of children and adolescents, ages 6–17. [ 3 ]
SSRIs are the most widely prescribed antidepressants in many countries. [3] The efficacy of SSRIs in mild or moderate cases of depression has been disputed [4] and may or may not be outweighed by side effects, especially in adolescent populations. [5] [6] [7] [8]