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There are no known significant drug interactions with topical clotrimazole. However, with oral (troche) clotrimazole, there are multiple interactions as the medication is a CYP450 enzyme inhibitor, primarily CYP3A4. Thus, any medication that is metabolized by the CYP3A4 enzyme will potentially have elevated levels when oral clotrimazole is used.
Oral candidiasis (Acute pseudomembranous candidiasis), which is also known as oral thrush, among other names, [1] is candidiasis that occurs in the mouth. That is, oral candidiasis is a mycosis (yeast/fungal infection) of Candida species on the mucous membranes of the mouth .
When two drugs affect each other, it is a drug–drug interaction (DDI). The risk of a DDI increases with the number of drugs used. [1] A large share of elderly people regularly use five or more medications or supplements, with a significant risk of side-effects from drug–drug interactions. [2] Drug interactions can be of three kinds:
Oral hygiene can help prevent oral candidiasis when people have a weakened immune system. [5] For people undergoing cancer treatment, chlorhexidine mouthwash can prevent or reduce thrush. [5] People who use inhaled corticosteroids can reduce the risk of developing oral candidiasis by rinsing the mouth with water or mouthwash after using the ...
That is, some azole drugs have adverse side-effects. Some azole drugs may disrupt estrogen production in pregnancy, affecting pregnancy outcome. [26] Oral fluconazole is not associated with a significantly increased risk of birth defects overall, although it does increase the odds ratio of tetralogy of Fallot, but the absolute risk is still low ...
Drug-drug interactions may occur when amphotericin B is coadministered with the following agents: [50] Flucytosine : Toxicity of flucytosine is increased and allows a lower dose of amphotericin B. Amphotericin B may also facilitate entry of flucystosine into the fungal cell by interfering with the permeability of the fungal cell membrane.
The article says drug users are at higher risk of oral thrush. This seems vague to me, what kind of drug is it referring to? It may be a lifestyle thing - IV drug users are not known for having a particularly wholesome diet and often exposed to the elements. Alternatively, it could be that needle-sharing has led to AIDS. But the reference is ...
Thrush, a common condition caused by overgrowth of the fungus Candida albicans. Cases are characterized by growth of matted, yellow-white patches of fungus in the mouth. Oral microbiology is the study of the microorganisms (microbiota) of the oral cavity and their interactions between oral microorganisms or with the host. [1]