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The derivative triamcinolone acetonide is the active ingredient in various topical skin preparations (cream, lotion, ointment, aerosol spray) designed to treat such skin conditions as rash, inflammation, redness, or intense itching due to eczema [15] and dermatitis. [16]
Triamcinolone acetonide, also known as 9α-fluoro-16α-hydroxyprednisolone 16α,17α-acetonide or as 9α-fluoro-11β,16α-17α,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone, is a synthetic halogenated cyclic ketal pregnane corticosteroid. [27] It is the C16α,17α acetonide of triamcinolone. [27]
Alclometasone dipropionate 0.05% (Aclovate cream, ointment) Triamcinolone acetonide 0.025% (Aristocort A cream, Kenalog lotion) Fluocinolone acetonide 0.01% (Capex shampoo, Dermasmooth) Desonide 0.05% (DesOwen cream, lotion)
The management of ear eczema will depend on the type of eczema diagnosed upon presentation. Generally, ear toileting and care are advised to help relieve symptoms. Washing the ears with an emollient and drying them is one way to achieve this. [2] Patients are advised against putting anything in the ears or scratching them. [2]
Topical glucocorticoids are used in the treatment of many skin conditions. They provide anti-inflammatory, antimitotic, and immune-system suppressing actions through various mechanisms. [1] Hydrocortisone cream is a type of topical glucocorticoid that is commonly found on the market.
Recently, in late 2014, phase 3 clinical trials were completed to evaluate treatments using Desonide cream versus amino acid moisturizing cream. [11] Patients with eczema or atopic dermatitis could be enrolled in this study, both male and female, over the age of 18. The randomized, double-blind, active control, 5-week study compared the effects ...