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Cisapride is a gastroprokinetic agent, a drug that increases motility in the upper gastrointestinal tract. It acts directly as a serotonin 5-HT 4 receptor agonist and indirectly as a parasympathomimetic .
This list is not limited to drugs that were ever approved by the FDA. Some of them (lumiracoxib, rimonabant, tolrestat, ximelagatran and ximelidine, for example) were approved to be marketed in Europe but had not yet been approved for marketing in the US, when side effects became clear and their developers pulled them from the market.
A drug recall removes a prescription or over-the-counter drug from the market. Drug recalls in the United States are made by the FDA or the creators of the drug when certain criteria are met. When a drug recall is made, the drug is removed from the market and potential legal action can be taken depending on the severity of the drug recall. [1]
Prucalopride, a first in class dihydro-benzofuran-carboxamide, is a selective, high affinity serotonin (5-HT 4) receptor agonist with enterokinetic activities. [29] Prucalopride alters colonic motility patterns via serotonin 5-HT 4 receptor stimulation: it stimulates colonic mass movements, which provide the main propulsive force for defecation .
“Studies have shown that women with PCOS are more likely to experience sexual dysfunction, including lower sex drive, arousal, lubrication, orgasm and satisfaction.” Over on the male side, Dr ...
The FDA said the recall of the device BioZorb Marker, initiated by Hologic in March, was not a product removal, but a correction. The agency also urged patients to report any side effects they ...
The affinity of cisapride for 5-HT 4 receptors in the heart has been implicated in the undesirable cardiac effects of cisapride itself. [ medical citation needed ] The conclusion of this study revealed that itopride is devoid of any abnormal effect on QT interval .
This isn’t the first time a product has been voluntarily recalled over benzene. In July 2021, Johnson & Johnson issued a recall of five Neutrogena aerosol sunscreens after detecting low levels ...