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Multiple myeloma is the second-most prevalent blood cancer (10%) after non-Hodgkin's lymphoma. [154] It represents about 1.8% of all new cancers and 2.1% of all cancer deaths. [7] Multiple myeloma affects slightly more men than women.
multiple myeloma Reduced production ( hypogammaglobulinemia ), as well as increased protein loss ( nephrotic syndrome , protein-losing enteropathy ), can cause hypoproteinemia. To determine the reason behind the lower serum total protein, a serum protein electrophoresis ought to be carried out.
Monoclonal gammopathy, also known as paraproteinemia, is the presence of excessive amounts of myeloma protein or monoclonal gamma globulin in the blood. It is usually due to an underlying immunoproliferative disorder or hematologic neoplasms, especially multiple myeloma. It is sometimes considered equivalent to plasma cell dyscrasia.
Osteolytic lesion at the bottom of the radius, diagnosed by a darker section that indicates a loss of bone density. An osteolytic lesion (from the Greek words for "bone" (ὀστέον), and "to unbind" (λύειν)) is a softened section of a patient's bone formed as a symptom of specific diseases, including breast cancer and multiple myeloma.
Multiple myeloma forms in plasma, or white blood cells, which help the immune system fight infections by creating antibodies that attack invasive germs, according to the Mayo Clinic. Cancerous ...
Some people can even end up getting a compression fracture of the spine while doing something as simple as carrying grocery bags, which would raise suspicion for multiple myeloma, Grajales-Cruz says.
The abdomen, the central nervous system, and the organs (including the lungs) are typically spared, but the extravasation in the extremities is sufficiently massive to cause circulatory shock and compartment syndromes, with a dangerous hypotension (low blood pressure), hemoconcentration (thickening of the blood) and hypoalbuminemia (drop in ...
Around 35,000 multiple myeloma cases are reported each year in the U.S. Older adults, men and people with obesity have a higher risk of the disease, though doctors are still trying to understand ...