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MGUS is a relatively stable condition afflicting 3% of people aged 50 and 5% of people aged 70; it progresses to multiple myeloma at a rate of 0.5–1% cases per year; smoldering multiple myeloma does so at a rate of 10% per year for the first 5 years, but then falls off sharply to 3% per year for the next 5 years and thereafter to 1% per year.
Erythema multiforme (EM) is a skin condition that appears with red patches evolving into target lesions, typically on both hands. [2] [3]It is a type of erythema possibly mediated by deposition of immune complexes (mostly IgM-bound complexes) in the superficial microvasculature of the skin and oral mucous membrane that usually follows an infection or drug exposure.
multiple myeloma Reduced production ( hypogammaglobulinemia ), as well as increased protein loss ( nephrotic syndrome , protein-losing enteropathy ), can cause hypoproteinemia. To determine the reason behind the lower serum total protein, a serum protein electrophoresis ought to be carried out.
Osteolytic lesion at the bottom of the radius, diagnosed by a darker section that indicates a loss of bone density. An osteolytic lesion (from the Greek words for "bone" (ὀστέον), and "to unbind" (λύειν)) is a softened section of a patient's bone formed as a symptom of specific diseases, including breast cancer and multiple myeloma.
Some people can even end up getting a compression fracture of the spine while doing something as simple as carrying grocery bags, which would raise suspicion for multiple myeloma, Grajales-Cruz says.
Around 35,000 multiple myeloma cases are reported each year in the U.S. Older adults, men and people with obesity have a higher risk of the disease, though doctors are still trying to understand ...
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