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The roles of non-coding RNAs: Ribonucleoproteins are shown in red, non-coding RNAs in blue. A non-coding RNA ( ncRNA ) is a functional RNA molecule that is not translated into a protein . The DNA sequence from which a functional non-coding RNA is transcribed is often called an RNA gene .
U6 snRNA is the non-coding small nuclear RNA (snRNA) component of U6 snRNP (small nuclear ribonucleoprotein), an RNA-protein complex that combines with other snRNPs, unmodified pre-mRNA, and various other proteins to assemble a spliceosome, a large RNA-protein molecular complex that catalyzes the excision of introns from pre-mRNA.
A non-specific immune cell is an immune cell (such as a macrophage, neutrophil, or dendritic cell) that responds to many antigens, not just one antigen.Non-specific immune cells function in the first line of defense against infection or injury.
Short interspersed nuclear elements (SINEs) are non-autonomous, non-coding transposable elements (TEs) that are about 100 to 700 base pairs in length. [1] They are a class of retrotransposons , DNA elements that amplify themselves throughout eukaryotic genomes , often through RNA intermediates.
Members of the Argonaute (Ago) protein family are central to RISC function. Argonautes are needed for miRNA-induced silencing and contain two conserved RNA binding domains: a PAZ domain that can bind the single stranded 3' end of the mature miRNA and a PIWI domain that structurally resembles ribonuclease-H and functions to interact with the 5 ...
Intermediate filaments are composed of a family of related proteins sharing common structural and sequence features. Initially designated 'intermediate' because their average diameter (10 nm ) is between those of narrower microfilaments (actin) and wider myosin filaments found in muscle cells, the diameter of intermediate filaments is now ...
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[11] [verification needed] [12] [13] This has led many texts to delineate between membrane-bounded and non-membrane bounded organelles. [14] The non-membrane bounded organelles, also called large biomolecular complexes , are large assemblies of macromolecules that carry out particular and specialized functions, but they lack membrane boundaries.