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The Hershey–Chase experiments were a series of experiments conducted in 1952 [1] by Alfred Hershey and Martha Chase that helped to confirm that DNA is genetic material.
Martha Cowles Chase (November 30, 1927 – August 8, 2003), also known as Martha C. Epstein, [1] was an American geneticist who in 1952, with Alfred Hershey, experimentally helped to confirm that DNA rather than protein is the genetic material of life.
The Hershey–Chase experiments were conducted by Alfred Hershey and Martha Chase in 1952 using the T2 bacteriophage (pictured), which is composed of DNA wrapped in a protein shell. Hershey and Chase labelled either the phage DNA using radioactive phosphorus-32 or the protein using radioactive sulphur-35.
Hershey–Chase experiment proves that phage genetic material is DNA. 1952: The Hershey–Chase experiment proves the genetic information of phages (and, by implication, all other organisms) to be DNA. [29] 1952: an X-ray diffraction image of DNA was taken by Raymond Gosling in May 1952, a student supervised by Rosalind Franklin. [30]
Experiments conducted in 1952 by Alfred Hershey and Martha Chase demonstrated how the DNA of viruses is injected into the bacterial cells, while most of the viral proteins remain outside. [1] [2] The injected DNA molecules cause the bacterial cells to produce more viral DNA and proteins. These discoveries supported that DNA, rather than ...
In 1952, Alfred Hershey and Martha Chase confirmed that the genetic material of the bacteriophage, the virus which infects bacteria, is made up of DNA [4] (see Hershey–Chase experiment). In 1953, James Watson and Francis Crick discovered the double helical structure of the DNA molecule based on the discoveries made by Rosalind Franklin. [5]
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Hershey was born in Owosso, Michigan to Robert Day and Alma Wilbur Hershey. He earned a B.S. in chemistry in 1930, and Ph.D. in bacteriology in 1934 from Michigan State University. Shortly after, Hershey accepted a faculty position at Washington University in St. Louis, [1] [2] serving as an instructor of bacteriology and immunology from 1934 ...