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He is also the medical director of the Spina Bifida Association of America. Brei's research has focused on healthcare outcomes for children with spina bifida and as an adult with spina bifida who is an uncommon leader, he has also served as an advocate. Brei has received extensive recognition for his work in developmental pediatrics.
Pierre Robin sequence [a] (/ p j ɛər r ɔː ˈ b æ̃ /; [3] abbreviated PRS) is a congenital defect observed in humans which is characterized by facial abnormalities.The three main features are micrognathia (abnormally small mandible), which causes glossoptosis (downwardly displaced or retracted tongue), which in turn causes breathing problems due to obstruction of the upper airway.
Spina bifida occulta means hidden split spine. [20] In this type of neural tube defect, the meninges do not herniate through the opening in the spinal canal. [19] The most frequently seen form of spina bifida occulta is when parts of the bones of the spine, called the spinous process, and the neural arch appear abnormal on a radiogram, without ...
Medical imaging can confirm the diagnosis after birth. [5] Spina bifida is a type of neural tube defect related to but distinct from other types such as anencephaly and encephalocele. [13] Most cases of spina bifida can be prevented if the mother gets enough folate before and during pregnancy. [3]
About 1 in 2,875 babies is born with spina bifida in the United States each year, according to the Centers for Disease Control and Prevention.
Spina bifida is a neural tube defect that involves defects in the development of the spine, and it can cause hydrocephalus. Myelomeningocele is the most severe type of spina bifida, involving an open spinal column and the exact mechanism of hydrocephalus involved in this condition is unclear.
[7] Most sacral dimple cases are minor and do not relate to any underlying medical problem, [1] [3] [5] but some can result from disease, notably spina bifida. [3] [5] If so, this is usually the spina bifida occulta form, which is the least serious kind. [3] Simple dimples are typically small, measuring less than 5 mm in size.
Therefore, effective management of CLP involves a wide range of specialists. The current model for delivery of this care is the multidisciplinary cleft team. This is a group of individuals from different specialist backgrounds who work closely together to provide patients with comprehensive care from birth through adolescence.