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p-Phenylenediamine (PPD) is an organic compound with the formula C 6 H 4 (NH 2) 2. This derivative of aniline is a white solid, but samples can darken due to air oxidation. [ 1 ] It is mainly used as a component of engineering polymers and composites like kevlar .
Selinexor sold under the brand name Xpovio among others, is a selective inhibitor of nuclear export used as an anti-cancer medication.It works by blocking the action of exportin 1 [6] and thus blocking the transport of several proteins involved in cancer-cell growth from the cell nucleus to the cytoplasm, which ultimately arrests the cell cycle and leads to apoptosis. [8]
Non-small cell lung cancer, oesophageal cancer, uterine cervical cancer, head and neck cancer and urothelial cancer: Nephrotoxicity, myelosuppression and nausea and vomiting (30-90%). Oxaliplatin: IV: Reacts with DNA, inducing apoptosis, non-cell cycle specific. Colorectal cancer, oesophageal cancer and gastric cancer
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Phenylenediamine may refer to: o-phenylenediamine or OPD, a chemical compound C 6 H 4 (NH 2) 2; m-phenylenediamine or MPD, a chemical compound C 6 H 4 (NH 2) 2; p-phenylenediamine or PPD, a chemical compound C 6 H 4 (NH 2) 2; N,N-dimethyl-p-phenylenediamine or DMPD; N,N,N′,N′-tetramethyl-p-phenylenediamine or TMPD, used in microbiology; N,N ...
6PPD is an organic chemical widely used as stabilising additive (or antidegradant) in rubbers, such as NR, SBR and BR; all of which are common in vehicle tires. [1] Although it is an effective antioxidant it is primarily used because of its excellent antiozonant performance.
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