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Xenon Xe 129 hyperpolarized, sold under the brand name Xenoview, is a hyperpolarized contrast agent indicated for use with magnetic resonance imaging (MRI) for evaluation of lung ventilation, and approved for people aged twelve years of age and older. [4] [5] It was approved for medical use in the US in December 2022. [6]
The hyperpolarization method called spin-exchange optical pumping (SEOP) is being used to hyperpolarize noble gases such as Xenon-129 and Helium-3. When an inhaled hyperpolarized gas like 3He or 129Xe is imaged, there is a higher magnetization density of NMR-active molecules in the lung compared to traditional 1H imaging, which improves the MRI ...
Compared with solar xenon, Earth's atmospheric Xe is enriched in heavy isotopes by 3 to 4% per atomic mass unit (amu). [18] However, the total abundance of xenon gas is depleted by one order of magnitude relative to other noble gases. [15] The elemental depletion while relative enrichment in heavy isotopes is called the "Xenon paradox".
Xenon-136 is an isotope of xenon that undergoes double beta decay to barium-136 with a very long half-life of 2.11 × 10 21 years, more than 10 orders of magnitude longer than the age of the universe ((13.799 ± 0.021) × 10 9 years). It is being used in the Enriched Xenon Observatory experiment to search for neutrinoless double beta decay.
Xenon has been used as a general anesthetic, but it is more expensive than conventional anesthetics. [154] Xenon interacts with many different receptors and ion channels, and like many theoretically multi-modal inhalation anesthetics, these interactions are likely complementary. Xenon is a high-affinity glycine-site NMDA receptor antagonist. [155]
Bio-FETs couple a transistor device with a bio-sensitive layer that can specifically detect bio-molecules such as nucleic acids and proteins. A Bio-FET system consists of a semiconducting field-effect transistor that acts as a transducer separated by an insulator layer (e.g. SiO 2) from the biological recognition element (e.g. receptors or probe molecules) which are selective to the target ...
Biosensors based on type of biotransducers. A biotransducer is the recognition-transduction component of a biosensor system. It consists of two intimately coupled parts; a bio-recognition layer and a physicochemical transducer, which acting together converts a biochemical signal to an electronic or optical signal.
Stability of miRNA Biosensor: The stability of miRNA biosensors is compromised by environmental conditions, particularly for components like aptamers and antibodies. This issue is especially pertinent for point-of-care (POC) devices, which require robustness and longevity to be effectively used in various settings.