Ads
related to: baclofen effect on sleep studycompare.smarter-choices.com has been visited by 100K+ users in the past month
Search results
Results From The WOW.Com Content Network
Baclofen, sold under the brand name Lioresal among others, is a medication used to treat muscle spasticity, such as from a spinal cord injury or multiple sclerosis. [8] [9] It may also be used for hiccups and muscle spasms near the end of life, [9] and off-label to treat alcohol use disorder [10] [11] or opioid withdrawal symptoms. [12]
[69] [70] Baclofen withdrawal can be more intense if it is administered intrathecally or for long periods of time. If baclofen or phenibut is used for long periods of time, it can resemble intense benzodiazepine, GHB, or alcohol withdrawal. To minimize withdrawal symptoms, baclofen or phenibut should be tapered down slowly.
Baclofen was first suggested as an adjunct because benzodiazepines do not affect GABA B receptors and therefore have no cross-tolerance with GHB while baclofen, which works via GABA B receptors, is cross-tolerant with GHB and may be more effective in alleviating withdrawal effects of GHB.
By contrast, other studies have indicated that the effects of sleep deprivation on cognitive performance, specifically sustained visual attention, are more global and bilateral in nature (as opposed to more lateralized deficit explanations). In a study using the Choice Visual Perception Task, subjects were exposed to stimuli appearing in ...
Baclofen also inhibits neural function presynaptically, by reducing calcium ion influx, and thereby reducing the release of excitatory neurotransmitters in both the brain and spinal cord. It may also reduce pain in patients by inhibiting the release of substance P in the spinal cord, as well.
Zolpidem tartrate, a common but potent sedative–hypnotic drug.Used for severe insomnia. Hypnotic (from Greek Hypnos, sleep [1]), or soporific drugs, commonly known as sleeping pills, are a class of (and umbrella term for) psychoactive drugs whose primary function is to induce sleep [2] (or surgical anesthesia [note 1]) and to treat insomnia (sleeplessness).