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Tricho-hepato-enteric syndrome (THE), also known as syndromic or phenotypic diarrhea, is an extremely rare congenital bowel disorder which manifests itself as intractable diarrhea in infants with intrauterine growth retardation, and hair and facial abnormalities. [2] Many also have liver disease and abnormalities of the immune system. [2]
Congenital tufting enteropathy is an inherited disorder of the small intestine that presents with intractable diarrhea in young children. Signs and symptoms The ...
It is characterized by chronic, intractable diarrhea in new-born infants, starting in the first few days of life. [3] This results in metabolic acidosis and severe dehydration. Pregnancy and birth are usually normal. [citation needed]
Lactose intolerance should be excluded in infants with intractable diarrhea. Like autoimmune enteropathy, lactose intolerance can affect the whole GI tract with primary findings in the small bowel. Biopsy reveals prominent mononuclear cell infiltrate of the lamina propria, reveal flattened villi, and edema.
Chronic diarrhea (alternate spelling: diarrhoea) of infancy, also called toddler's diarrhea, is a common condition typically affecting up to 1.7 billion children between ages 6–30 months worldwide every year, usually resolving by age 4.
[2] [3] The chronic condition is diagnosed in approximately 10% of postcholecystectomy cases. The pain associated with postcholecystectomy syndrome is usually ascribed to either sphincter of Oddi dysfunction or to post-surgical adhesions. [4] A recent 2008 study shows that postcholecystectomy syndrome can be caused by biliary microlithiasis. [5]
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The classical triad describes the most common symptoms of IPEX: intractable diarrhea, type 1 diabetes, and eczema. Symptoms usually begin shortly after birth. [12] Other symptoms include: thyroid disease, kidney dysfunction, blood disorders, frequent infections, autoimmune hemolytic anemia, and food allergies, among others. [10]